[Monotherapy of epilepsy in women: psychiatric and neuroendocrine aspects] Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov [Zh Nevrol Psikhiatr Im S S Korsakova] Journal article

Title	[Monotherapy of epilepsy in women: psychiatric and neuroendocrine aspects]
Author(s)	Zheleznova EV, Kalinin VV, Zemlianaia AA, Sokolova LV, Medvedev IL
Source	Zh Nevrol Psikhiatr Im S S Korsakova 2008; 108(10):43-8.
MeSH	Adult Anticonvulsants Dose-Response Relationship, Drug Epilepsy Female Follow-Up Studies Gonadal Steroid Hormones Humans Psychometrics Treatment Outcome
Abstract	An aim of the study was a comparative evaluation of efficacy and safety of traditional and modern antiepileptic drugs in women of reproductive age. A main group of patients consisted of 65 women, including 48 patients with partial epilepsy and 17 - with idiopathic generalized epilepsy. Some issues are solved in the study of a larger group comprising 110 patients (65 female and 45 male). The following drugs have been studied: topamax, valproates, carbamazepines and barbiturates. All of them were used as a monotherapy. Patient's state was assessed using clinical, neuropsychological and hormonal parameters. A general conclusion is that topamax is most beneficial, comparing with other drugs studied, in the treatment of women with epilepsy.
Language	rus
Pub Type(s)	Comparative Study English Abstract Journal Article
PubMed ID	19008851

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